Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699830 | 0.89 | KDM4E (0.65) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29827495 | 0.81 | KDM4E (0.71) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29827647 | 0.81 | KDM4E (0.64) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29827757 | 0.81 | KDM4E (0.60) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL13700089 | 0.80 | KDM4E (0.52) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29827625 | 0.79 | KDM4E (0.61) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4926041 | 0.78 | KDM4E (1.00) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29827374 | 0.77 | KDM4E (0.69) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29827612 | 0.77 | KDM4E (0.73) | KDM4EMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL4251178 | 0.76 | ALDH1A1 (0.72) | KDM4EMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773302-B | Benzofuran derivative and medical application thereof | 中国药科大学 | 2024-04-02 | — | — | CN | disclosed |