Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | CPA2 | P48052 | 1/20 | 0.45 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396098 | 0.90 | GNPAT (0.60) | GNPATSIRT6SIRT1FOLH1CPA1 | |
| SCHEMBL29394494 | 0.90 | GNPAT (0.60) | GNPATSIRT6SIRT1FOLH1CPA1 | |
| SCHEMBL29396725 | 0.90 | GNPAT (0.60) | GNPATSIRT6SIRT1FOLH1CPA1 | |
| SCHEMBL29517462 | 0.87 | GNPAT (0.54) | GNPATSIRT6SIRT1ECE1FOLH1 | |
| SCHEMBL29510666 | 0.86 | GNPAT (0.52) | GNPATSIRT6SIRT1ECE1FOLH1 | |
| SCHEMBL11951539 | 0.86 | FOLH1 (0.49) | GNPATSIRT6SIRT1ECE1FOLH1 | |
| SCHEMBL30924954 | 0.86 | GSR (0.49) | ECE1FOLH1CPB2 | |
| SCHEMBL32679339 | 0.85 | SIRT6 (0.55) | GNPATSIRT6SIRT1FOLH1CPA1 | |
| SCHEMBL30731554 | 0.84 | FOLH1 (0.48) | GNPATECE1FOLH1CPB2 | |
| Acetic Acid SCHEMBL10767009 | 0.84 | SIRT6 (0.53) | GNPATSIRT6SIRT1FOLH1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117925757-A | Asparagine endopeptidase mediated polypeptide cyclization method and application thereof in phage display peptide library | 安徽大学 | 2024-04-26 | — | — | CN | disclosed |