SCHEMBL30874089

SCHEMBL30874089

OCc1cc(-c2ccccc2)c(Oc2ccc3cc(-c4ccccc4)ccc3c2-c2c(Oc3c(-c4ccccc4)cc(CO)c4ccccc34)ccc3cc(-c4ccccc4)ccc23)c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
GPR84 Q9NQS5 5/20 0.39
HSD17B1 P14061 3/20 0.39
HSD17B2 P37059 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2B6 P20813 2/20 0.39
CYP2C19 P33261 2/20 0.39
MTNR1A P48039 2/20 0.33
MTNR1B P49286 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PDE5A O76074 1/20 0.33
PDE4A P27815 1/20 0.33
PDE1A P54750 1/20 0.33
PDE1B Q01064 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30873984 0.96 GPR84 (0.41) ESR1ESR2GPR84HSD17B1HSD17B2
SCHEMBL30874006 0.93 GPR84 (0.41) ESR1ESR2GPR84HSD17B1HSD17B2
SCHEMBL30874040 0.91 SLC6A9 (0.41) ESR1ESR2GPR84HSD17B1HSD17B2
SCHEMBL30874076 0.90 MAPT (0.41) GPR84KDM4EMEN1KMT2APDE5A
SCHEMBL30873985 0.90 PPARG (0.38) GPR84HSD17B1HSD17B2CYP1A2CYP3A4
SCHEMBL30874008 0.86 GPR84 (0.38) GPR84CYP2C9CYP2C19MTNR1AMTNR1B
SCHEMBL30874110 0.86 SLC6A9 (0.36) GPR84HSD17B1HSD17B2CYP1A2CYP3A4
SCHEMBL30874114 0.84 ESR1 (0.45) ESR1ESR2GPR84HSD17B1HSD17B2
SCHEMBL30873992 0.82 ESR1 (0.46) ESR1ESR2GPR84HSD17B1HSD17B2
SCHEMBL30874031 0.81 ESR1 (0.43) ESR1ESR2GPR84HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594286-A1 OLIGOMERIC BINAPHTYL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-08-06 EP disclosed
WO-2024068860-A1 OLIGOMERIC BINAPHTYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2024-04-04 WO disclosed