Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26509089 | 0.90 | MEN1 (0.46) | ACACBCRBNDDB1MEN1KMT2A | |
| SCHEMBL30148829 | 0.89 | CRBN (0.42) | ACACBCRBNDDB1MEN1KMT2A | |
| SCHEMBL23122937 | 0.88 | CRBN (0.42) | CRBNDDB1MEN1KMT2ALMNA | |
| SCHEMBL30009009 | 0.88 | CRBN (0.42) | CRBNDDB1MEN1KMT2ALMNA | |
| SCHEMBL30267149 | 0.86 | CRBN (0.47) | CRBNDDB1MEN1KMT2AGABRD | |
| SCHEMBL21409346 | 0.85 | GABRD (0.57) | CRBNDDB1GABRDGABRA1GABRB1 | |
| SCHEMBL26101474 | 0.84 | ACACB (0.47) | ACACBCRBNDDB1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31138067 | 0.84 | GABRD (0.56) | CRBNDDB1GABRDGABRA1GABRB1 | |
| SCHEMBL30995357 | 0.84 | CRBN (0.38) | ACACBCRBNDDB1MEN1KMT2A | |
| SCHEMBL29319120 | 0.84 | CRBN (0.38) | ACACBCRBNDDB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4166557-B1 | INTERMEDIATES OF N-(3-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)BENZAMIDE DERIVATIVES | NOVARTIS AG (CH) | 2026-05-06 | — | — | EP | disclosed |
| CN-118754858-A | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111936498-B | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-04-16 | — | — | CN | disclosed |