Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21409346 | 0.90 | GABRD (0.57) | CRBNDDB1GABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL31138067 | 0.89 | GABRD (0.56) | CRBNDDB1GABRDGABRA1GABRB1 | |
| SCHEMBL30014739 | 0.87 | MAPK1 (0.41) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL30014819 | 0.87 | HPGD (0.43) | GABRDGABRA1GABRB1GABRA5GABRA3 | |
| SCHEMBL31722503 | 0.87 | CHRM2 (0.43) | CRBNDDB1GABRDGABRA1GABRB1 | |
| SCHEMBL25904549 | 0.86 | NR3C1 (0.44) | CRBNDDB1HPGDTSHRCYP3A4 | |
| SCHEMBL30874149 | 0.86 | ACACB (0.45) | CRBNDDB1GABRDGABRA1GABRB1 | |
| SCHEMBL30266960 | 0.86 | CRBN (0.42) | CRBNDDB1GABRDGABRA1GABRB1 | |
| SCHEMBL28978031 | 0.86 | CRBN (0.42) | CRBNDDB1GABRDGABRA1GABRB1 | |
| SCHEMBL31722747 | 0.85 | CHRM2 (0.42) | CRBNDDB1GABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025159-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |