Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.52 |
| ▸ | TNKS | O95271 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160700 | 0.88 | CRBN (0.65) | DDB1CRBNALDH1A1POLBATM | |
| SCHEMBL25575695 | 0.88 | CRBN (0.65) | DDB1CRBNALDH1A1POLBATM | |
| Trifluoroacetic Acid SCHEMBL30874165 | 0.82 | PKM (0.39) | DDB1CRBNPOLBKDM4E | |
| Trifluoroacetic Acid SCHEMBL31630912 | 0.80 | PKM (0.43) | DDB1CRBNDRD2 | |
| SCHEMBL25905651 | 0.79 | CRBN (0.56) | DDB1CRBNTNKSTNKS2 | |
| Trifluoroacetic Acid SCHEMBL31255479 | 0.78 | PKM (0.57) | CRBNALDH1A1POLBKDM4E | |
| Trifluoroacetic Acid SCHEMBL31255164 | 0.78 | PKM (0.60) | ALDH1A1POLBKDM4E | |
| SCHEMBL25653902 | 0.76 | CRBN (0.48) | DDB1CRBNATMKDM4E | |
| SCHEMBL23120569 | 0.75 | CA12 (0.48) | DDB1CRBNALDH1A1KDM4E | |
| SCHEMBL21408886 | 0.75 | KDM4E (0.50) | DDB1CRBNALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936498-B | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-04-16 | — | — | CN | disclosed |