Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697005 | 1.00 | SIRT6 (0.55) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL23680085 | 0.87 | KDM4E (0.43) | SIRT6TSHRKMT2AP4HTMLMNA | |
| SCHEMBL2635320 | 0.83 | SIRT6 (0.73) | SIRT6ADORA3TSHRMC4RADRA1A | |
| Hydrochloric Acid SCHEMBL27917292 | 0.81 | SIRT6 (0.70) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL20863062 | 0.81 | SIRT6 (0.53) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL5903167 | 0.78 | CCR1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL29684052 | 0.78 | SIRT6 (0.50) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL17712841 | 0.77 | SIRT6 (0.64) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL14592876 | 0.76 | SIRT6 (0.53) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL991320 | 0.76 | MAPK1 (0.49) | SIRT6LCKLMNACYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453764-B | 7H-pyrrolo [2,3-d ] pyrimidin-4-amine derivatives | 大鹏药品工业株式会社 | 2024-04-16 | — | — | CN | disclosed |