SCHEMBL2635320

SCHEMBL2635320

NC(=O)c1cnc(C(N)=O)cn1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIRT6 Q8N6T7 3/20 0.73
▸ ADORA3 P0DMS8 1/20 0.61
▸ TSHR P16473 1/20 0.61
▸ MC4R P32245 1/20 0.61
▸ ADRA1A P35348 1/20 0.61
▸ MC3R P41968 1/20 0.61
▸ KMT2A Q03164 1/20 0.50
▸ LMNA P02545 1/20 0.44
▸ LCK P06239 1/20 0.44
▸ P4HTM Q9NXG6 3/20 0.42
▸ P4HA1 P13674 1/20 0.42
▸ MIF P14174 1/20 0.42
▸ KDM4E B2RXH2 3/20 0.41
▸ NNMT P40261 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ GSK3B P49841 1/20 0.39
▸ NAPRT Q6XQN6 1/20 0.39
▸ HCAR2 Q8TDS4 1/20 0.39
▸ ASPH Q12797 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27917292 0.97 SIRT6 (0.70) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL17712841 0.92 SIRT6 (0.64) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL2220140 0.87 SIRT6 (0.59) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL5041030 0.87 SIRT6 (0.59) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL30489429 0.87 SIRT6 (0.59) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL29757816 0.85 SIRT6 (0.57) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL147506 0.85 SIRT6 (0.57) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL2024145 0.85 SIRT6 (0.57) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL31041116 0.85 SIRT6 (1.00) SIRT6ADORA3TSHRMC4RADRA1A
SCHEMBL29844782 0.85 SIRT6 (0.57) SIRT6ADORA3TSHRMC4RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4314766-A1 METHODS OF MONITORING MUCOSAL HEALING Medibeacon Inc. (US) 2024-02-07 — — EP claimed
US-20220326255-A1 METHODS OF MONITORING MUCOSAL HEALING MEDIBEACON INC. 2022-10-13 — — US claimed
WO-2022212510-A1 METHODS OF MONITORING MUCOSAL HEALING MEDIBEACON INC. (US) 2022-10-06 — — WO claimed
CN-105189506-A Compounds and compositions for the treatment of parasitic diseases NOVARTIS AG 2015-12-23 — — CN claimed
EP-3700578-B1 SYSTEMS FOR RENAL FUNCTION DETERMINATION MEDIBEACON INC (US) 2025-12-03 — — EP disclosed
US-12303570-B2 Compositions and methods for assessing eye vasculature MEDIBEACON INC. (US) 2025-05-20 — — US disclosed
CN-114555087-B Anodic oxidation of 5-aminouracil 麦迪贝肯有限公司 2025-04-18 — — CN disclosed
EP-3917378-B1 SYSTEMS AND METHODS FOR HOME TRANSDERMAL GFR MONITORING MEDIBEACON INC (US) 2025-01-08 — — EP disclosed
US-12102432-B2 Uses of transdermal glomerular filtration rate measurement in continuous renal replacement therapy MEDIBEACON, INC. (US) 2024-10-01 — — US disclosed
EP-4314766-A1 METHODS OF MONITORING MUCOSAL HEALING Medibeacon Inc. (US) 2024-02-07 — — EP disclosed
CN-117120826-A Method for monitoring mucosal healing 麦迪贝肯有限公司 2023-11-24 — — CN disclosed
EP-4243879-A1 SUBCUTANEOUS AND INTRAMUSCULAR ADMINISTRATION OF PYRAZINE COMPOUNDS Medibeacon Inc. (US) 2023-09-20 — — EP disclosed
WO-2016183351-A1 COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE MEDIBEACON INC. (US) 2016-11-17 — — WO disclosed
CN-105189506-A Compounds and compositions for the treatment of parasitic diseases NOVARTIS AG 2015-12-23 — — CN disclosed
WO-2011143540-A1 UNIFORM, FUNCTIONALIZED, CROSS-LINKED NANOSTRUCTURES FOR MONITORING pH MALLINCKRODT LLC (US) 2011-11-17 — — WO disclosed
EP-2217281-A2 PHOTONIC SHELL-CORE CROSS LINKED AND FUNCTIONALIZED NANOSTRUCTURES FOR BIOLOGICAL APPLICATIONS Mallinckrodt Inc. (US) 2010-08-18 — — EP disclosed
EP-2131861-A2 INTEGRATED PHOTOACTIVE SMALL MOLECULES AND USES THEREOF Mallinckrodt Inc. (US) 2009-12-16 — — EP disclosed
WO-2009061473-A2 PHOTONIC SHELL-CORE CROSS LINKED AND FUNCTIONALIZED NANOSTRUCTURES FOR BIOLOGICAL APPLICATIONS MALLINCKRODT INC. (US) 2009-05-14 — — WO disclosed
WO-2008108944-A2 INTEGRATED PHOTOACTIVE SMALL MOLECULES AND USES THEREOF MALLINCKRODT INC. (US) 2008-09-12 — — WO disclosed
US-4871736-A ANTITUMOR AGENTS THE OHIO STATE UNIVERSITY (US) 1989-10-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12102432-B2 Uses of transdermal glomerular filtration rate measurement in continuous renal replacement therapy OGFR, PTGFR, PTAFR SIRT6 2136/4885ADORA3 758/4885TSHR 231/4885
US-20220326255-A1 METHODS OF MONITORING MUCOSAL HEALING FABP2, SI, SLC10A2 SIRT6 2693/4885ADORA3 3360/4885TSHR 3954/4885
US-12303570-B2 Compositions and methods for assessing eye vasculature LIPG, FLT4, FABP3 SIRT6 1284/4885ADORA3 874/4885TSHR 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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