Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525023 | 0.84 | KDM4E (0.53) | PIK3C3LMNAKDM5AKDM4CKDM5B | |
| SCHEMBL5700255 | 0.84 | ALDH1A1 (0.46) | PIK3C3ROCK1LMNAKDM5AKDM4C | |
| SCHEMBL20790368 | 0.84 | KDM4E (0.53) | PIK3C3LMNAKDM5AKDM4CKDM5B | |
| SCHEMBL943650 | 0.83 | LRRK2 (0.51) | MAP4K4LMNAKDM5AKDM4CKDM5B | |
| SCHEMBL22346451 | 0.81 | LMNA (0.40) | PIK3C3LMNAKDM5AKDM4CKDM5B | |
| SCHEMBL20791437 | 0.79 | ALDH1A1 (0.50) | PIK3C3LMNAKDM4C | |
| SCHEMBL6742155 | 0.79 | ALDH1A1 (0.40) | PIK3C3MAP4K4ROCK1LMNAKDM5A | |
| SCHEMBL5700227 | 0.79 | HRH4 (0.41) | PIK3C3ROCK1LMNALRRK2 | |
| SCHEMBL6742993 | 0.77 | KMT2A (0.53) | KDM5B | |
| SCHEMBL25261077 | 0.76 | NPSR1 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453764-B | 7H-pyrrolo [2,3-d ] pyrimidin-4-amine derivatives | 大鹏药品工业株式会社 | 2024-04-16 | — | — | CN | disclosed |