Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856562 | 0.91 | HRH3 (0.62) | HRH3CXCR4SMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL1859625 | 0.83 | HRH3 (0.60) | HRH3CXCR4SMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL5133060 | 0.82 | HRH3 (0.48) | HRH3KDM4ESIRT6GRM2 | |
| SCHEMBL3311748 | 0.81 | HIF1A (0.60) | HRH3SMN1; SMN2HIF1AEPAS1HTT | |
| SCHEMBL27815604 | 0.79 | HRH3 (0.61) | HRH3CXCR4SMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL15651024 | 0.78 | CXCR4 (0.69) | HRH3CXCR4SMN1; SMN2HTTKDM4E | |
| SCHEMBL16840950 | 0.78 | SMN1; SMN2 (0.51) | HRH3CXCR4SMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL1863041 | 0.77 | HRH3 (1.00) | HRH3 | |
| SCHEMBL11981676 | 0.76 | CXCR4 (0.51) | HRH3CXCR4SMN1; SMN2CYP2C9ALOX15 | |
| SCHEMBL5040368 | 0.75 | KMO (0.51) | HRH3SMN1; SMN2HTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453764-B | 7H-pyrrolo [2,3-d ] pyrimidin-4-amine derivatives | 大鹏药品工业株式会社 | 2024-04-16 | — | — | CN | disclosed |