SCHEMBL5040368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29889648	1.00	KMO (0.51)	KMOALDH1A1POLBHRH3PARP1
	SCHEMBL29907656	0.89	KMO (0.60)	KMOALDH1A1POLBHPGDPIK3CA
	SCHEMBL322646	0.89	KMO (0.60)	KMOALDH1A1POLBHPGDPIK3CA
	SCHEMBL17075525	0.87	KMO (0.59)	KMOALDH1A1POLBHPGDPIK3CA
	SCHEMBL27858848	0.87	ALDH1A1 (0.51)	KMOALDH1A1POLBHPGDPIK3CA
	SCHEMBL5041190	0.85	HRH3 (0.50)	ALDH1A1HRH3PARP1HPGDKDM4E
	SCHEMBL18412787	0.84	ALDH1A1 (0.49)	KMOALDH1A1POLBHPGDPIK3CA
	SCHEMBL29546455	0.83	HRH3 (0.49)	ALDH1A1HRH3PARP1HPGDKDM4E
	Lithium Ion SCHEMBL17075524	0.83	ALDH1A1 (0.49)	KMOALDH1A1POLBHPGDPIK3CA
	SCHEMBL5042063	0.81	HDAC3 (0.51)	HRH3SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.