SCHEMBL30874264

SCHEMBL30874264

CC1CCOC(=O)c2cccc(c2)C(=O)OCC1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 2/20 0.34
HSD11B1 P28845 2/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 2/20 0.33
HPGD P15428 1/20 0.33
MAP3K14 Q99558 1/20 0.33
GRM2 Q14416 1/20 0.32
MAPK1 P28482 1/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
RAB9A P51151 1/20 0.31
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23855448 0.86 HRH3 (0.33) ALDH1A1SMN1; SMN2NPC1TSHRLMNA
Adipic Acid SCHEMBL30361176 0.85 CNR2 (0.36) SMN1; SMN2NPC1RAB9A
SCHEMBL7783365 0.81 NPC1 (0.33) ALDH1A1NPC1
SCHEMBL102784 0.81 ITGB2 (0.38) ALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL14067104 0.81 ITGB2 (0.38) ALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL3179787 0.79 CLK1 (0.30) SMN1; SMN2
Lithium SCHEMBL30114456 0.79 ITGB2 (0.36) ALDH1A1SMN1; SMN2NPC1LMNA
Potassium SCHEMBL30808411 0.79 ITGB2 (0.36) ALDH1A1SMN1; SMN2NPC1LMNA
Hydrogen Sulfide SCHEMBL28295724 0.79 ITGB2 (0.36) ALDH1A1SMN1; SMN2NPC1LMNA
SCHEMBL18978129 0.79 CASP3 (0.33) ALDH1A1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4321552-A1 CARBONATE GROUP-CONTAINING POLYOL, POLYURETHANE RESIN COMPOSITION, ARTIFICIAL LEATHER, AND LEATHER-LIKE SHEET Asahi Kasei Kabushiki Kaisha (JP) 2024-02-14 EP disclosed