SCHEMBL7783365

SCHEMBL7783365

CC1CCCOC(=O)c2cccc(c2)C(=O)OC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32
MTOR P42345 1/20 0.30
ALDH1A1 P00352 1/20 0.30
FAAH O00519 1/20 0.30
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20222408 0.90 NPC1 (0.30) NPC1
SCHEMBL20222415 0.86
SCHEMBL30084350 0.83 MEN1 (0.31)
SCHEMBL28411162 0.82 KMT2A (0.32)
SCHEMBL30874264 0.81 ALDH1A1 (0.36) NPC1ALDH1A1
SCHEMBL20221752 0.80 PGR (0.32)
SCHEMBL18978129 0.79 CASP3 (0.33) NPC1ALDH1A1
SCHEMBL209608 0.78 CA1 (0.37) NPC1ALDH1A1FAAHNAAA
SCHEMBL212973 0.78 KMT2A (0.34) NPC1ALDH1A1FAAHNAAA
SCHEMBL719442 0.78 MAPK1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868548-B1 A PROCESS FOR MAKING MULTICOLORED YARNS DU PONT (US) 2001-10-10 EP disclosed
US-6098392-A Process for making multicolored yarns and the product thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-08-08 US disclosed
EP-0868548-A1 A PROCESS FOR MAKING MULTICOLORED YARNS AND THE PRODUCT THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-10-07 EP disclosed
WO-1997023674-A1 A PROCESS FOR MAKING MULTICOLORED YARNS AND THE PRODUCT THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-07-03 WO disclosed