SCHEMBL30874286

SCHEMBL30874286

Cc1ccc(S(=O)(=O)NC(F)(F)F)c(-c2c(C)cccc2C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.39
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
POLB P06746 1/20 0.38
ALOX12 P18054 1/20 0.38
GFER P55789 1/20 0.38
MCL1 Q07820 1/20 0.37
GAA P10253 2/20 0.36
SLC40A1 Q9NP59 3/20 0.36
FFAR1 O14842 1/20 0.35
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
CCNA2 P20248 1/20 0.35
CDK2 P24941 1/20 0.35
CDK7 P50613 1/20 0.35
CCNH P51946 1/20 0.35
CCNA1 P78396 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874282 0.76 MCL1 (0.39) MAPTALDH1A1MCL1FFAR4KMT2A
SCHEMBL30874284 0.76 ALOX5AP (0.37) MCL1ALOX5APFEN1
SCHEMBL30874279 0.74 MAOB (0.40) ALDH1A1HPGDSLC40A1FFAR4MAPK1
SCHEMBL10391681 0.73 FEN1 (0.46) POLBALOX5APFEN1
SCHEMBL31717860 0.70 GAA (0.36) PDK2MAPTALDH1A1HPGDPOLB
SCHEMBL22541454 0.69 ALDH1A1 (0.39) MAPTALDH1A1HPGDPOLBALOX12
SCHEMBL6163208 0.67 ALOX5AP (0.45) ALDH1A1ALOX5APFEN1
SCHEMBL699897 0.66 ALDH1A1 (0.46) PDK2MAPTALDH1A1HPGDGAA
SCHEMBL16261204 0.66 ALDH1A1 (0.54) MAPTALDH1A1HPGDPOLBALOX12
SCHEMBL16852673 0.65 ALDH1A1 (0.47) MAPTALDH1A1HPGDPOLBMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945956-A Synthesis method of N-trifluoromethyl sulfonamide compound 南京理工大学 2024-04-30 CN disclosed