Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874284 | 0.86 | ALOX5AP (0.37) | MCL1ALOX5APFEN1 | |
| SCHEMBL4848783 | 0.79 | AGTR1 (0.43) | AGTR1APPFLT1FLT4KDR | |
| SCHEMBL4616262 | 0.79 | AGTR1 (0.43) | AGTR1APPFLT1FLT4KDR | |
| SCHEMBL30874279 | 0.78 | MAOB (0.40) | FFAR4LMNAPTGS2ALDH1A1CNR1 | |
| SCHEMBL30874286 | 0.76 | PDK2 (0.39) | MCL1FFAR4MAPTALOX5APFEN1 | |
| SCHEMBL6163208 | 0.74 | ALOX5AP (0.45) | ALOX5APFEN1ALDH1A1 | |
| SCHEMBL19993838 | 0.72 | MEN1 (0.43) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6162420 | 0.71 | RXRA (0.43) | MAPTALOX5APFEN1MEN1KMT2A | |
| SCHEMBL6764348 | 0.70 | ALOX5AP (0.47) | ALOX5APFEN1CNR1 | |
| SCHEMBL6166229 | 0.69 | HPGD (0.48) | MAPTLMNAPTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945956-A | Synthesis method of N-trifluoromethyl sulfonamide compound | 南京理工大学 | 2024-04-30 | — | — | CN | disclosed |