Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK3 | P35626 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28769171 | 1.00 | GRK3 (0.33) | GRK3MRGPRX4SLC6A4KCNK3KCNK9 | |
| SCHEMBL27860909 | 0.83 | AR (0.35) | KCNK3KCNK9ARHCRTR1HCRTR2 | |
| SCHEMBL28219895 | 0.79 | RXRA (0.46) | MRGPRX4RXRARXRBRXRGPPARG | |
| SCHEMBL19756388 | 0.77 | MAPT (0.37) | GRK3MRGPRX4SLC6A4KCNK3KCNK9 | |
| SCHEMBL31037150 | 0.76 | MRGPRX4 (0.37) | GRK3MRGPRX4KCNK3KCNK9RXRA | |
| SCHEMBL31037145 | 0.76 | MRGPRX4 (0.34) | GRK3MRGPRX4SLC6A4KCNK3KCNK9 | |
| SCHEMBL31037148 | 0.76 | MRGPRX4 (0.37) | GRK3MRGPRX4KCNK3KCNK9RXRA | |
| SCHEMBL28594170 | 0.76 | TAAR1 (0.34) | MRGPRX4RXRARXRBRXRGPPARG | |
| SCHEMBL21376359 | 0.74 | PARP1 (0.39) | PARP1ARP2RX7 | |
| SCHEMBL28594168 | 0.74 | TAAR1 (0.35) | GRK3MRGPRX4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865771-A | Synthesis method of 2, 3-dichloro benzotrifluoride | 上海泰初化工技术有限公司 | 2024-04-12 | — | — | CN | disclosed |