Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676898 | 0.83 | PIM1 (0.36) | ARAPLNRKDM4EKCNK3KCNK9 | |
| SCHEMBL28769171 | 0.83 | GRK3 (0.33) | ARKCNK3KCNK9HCRTR1HCRTR2 | |
| SCHEMBL30874294 | 0.83 | GRK3 (0.33) | ARKCNK3KCNK9HCRTR1HCRTR2 | |
| SCHEMBL6679512 | 0.81 | ATM (0.39) | ARAPLNRKDM4EPTGS2 | |
| SCHEMBL28219895 | 0.74 | RXRA (0.46) | PTGS2 | |
| SCHEMBL6681359 | 0.73 | AR (0.41) | ARAPLNRKDM4EPTGS2 | |
| SCHEMBL19756388 | 0.73 | MAPT (0.37) | KCNK3KCNK9HCRTR1HCRTR2 | |
| SCHEMBL31037150 | 0.72 | MRGPRX4 (0.37) | KCNK3KCNK9HCRTR1HCRTR2 | |
| SCHEMBL31037148 | 0.72 | MRGPRX4 (0.37) | KCNK3KCNK9HCRTR1HCRTR2 | |
| SCHEMBL28995384 | 0.72 | AR (0.40) | ARAPLNRKDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703726-B | Trifluoromethyl phenyl sulfide compound | 上海泰初化工技术有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115703726-A | Trifluoromethyl phenyl sulfide compound | 上海泰初化工技术有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-112939818-B | Synthetic method of 2- (2, 2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 江苏扬农化工股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-112939818-A | Synthetic method of 2- (2, 2-difluoroethoxy) -6-trifluoromethylbenzenesulfonyl chloride | 江苏扬农化工股份有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-105801454-A | Method for preparation of 2-(2,2-difluoroethoxy)-6-(trifluoromethyl)benzene-1-sulfonyl chloride | 沈阳中化农药化工研发有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-102001979-B | Preparation method of 2-(2', 2'-difluoroethoxyl)-6-trifluoromethyl phenyl propyl sulfide | UNIV SHANGHAI ENG SCIENCE | 2013-07-31 | — | — | CN | disclosed |
| CN-102001979-B | Preparation method of 2-(2', 2'-difluoroethoxyl)-6-trifluoromethyl phenyl propyl sulfide | UNIV SHANGHAI ENG SCIENCE | 2013-07-31 | — | — | CN | disclosed |
| CN-102001979-A | Preparation method of 2-(2', 2'-difluoroethoxyl)-6-trifluoromethyl phenyl propyl sulfide | UNIV SHANGHAI ENG SCIENCE | 2011-04-06 | — | — | CN | disclosed |
| CN-102001979-A | Preparation method of 2-(2', 2'-difluoroethoxyl)-6-trifluoromethyl phenyl propyl sulfide | UNIV SHANGHAI ENG SCIENCE | 2011-04-06 | — | — | CN | disclosed |