SCHEMBL30874386

SCHEMBL30874386

CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CS)C(=O)O)C(C)C

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 2/20 0.58
▸ GRPR P30550 2/20 0.57
▸ NPBWR1 P48145 3/20 0.55
▸ IL23R Q5VWK5 6/20 0.55
▸ GLP1R P43220 4/20 0.53
▸ ECE1 P42892 1/20 0.53
▸ MUS81 Q96NY9 1/20 0.53
▸ PCSK9 Q8NBP7 1/20 0.52
▸ SLC2A1 P11166 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30637763 0.94 RXFP1 (0.61) RXFP1GRPRNPBWR1IL23RGLP1R
SCHEMBL30874393 0.94 RXFP1 (0.60) RXFP1GRPRNPBWR1IL23RGLP1R
SCHEMBL30598172 0.93 RXFP1 (0.63) RXFP1NPBWR1IL23RGLP1RECE1
SCHEMBL30578571 0.92 RXFP1 (0.58) RXFP1GRPRNPBWR1IL23RGLP1R
SCHEMBL30242111 0.92 IL23R (0.59) RXFP1NPBWR1IL23RPCSK9
SCHEMBL31453816 0.92 RXFP1 (0.65) RXFP1NPBWR1IL23RGLP1RECE1
SCHEMBL3113818 0.91 RXFP1 (0.54) RXFP1GRPRNPBWR1IL23RGLP1R
SCHEMBL30690354 0.90 RXFP1 (0.63) RXFP1GRPRIL23RGLP1RECE1
SCHEMBL29443912 0.89 RXFP1 (0.63) RXFP1GRPRIL23RGLP1RECE1
SCHEMBL30262147 0.89 IL23R (0.68) NPBWR1IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES Nanjing Finepeptide Biopharmaceutical Co.,Ltd (CN) 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES GLP1R, IAPP, GCG RXFP1 271/4885GRPR 36/4885NPBWR1 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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