Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.63 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.62 |
| ▸ | GLP1R | P43220 | 4/20 | 0.57 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.55 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.54 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453816 | 0.96 | RXFP1 (0.65) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30598132 | 0.93 | RXFP1 (0.64) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30874386 | 0.93 | RXFP1 (0.58) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30637763 | 0.93 | RXFP1 (0.61) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30874393 | 0.92 | RXFP1 (0.60) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30093113 | 0.92 | PCSK9 (0.61) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30093105 | 0.92 | PCSK9 (0.61) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30220493 | 0.92 | RXFP1 (0.65) | RXFP1NPBWR1GLP1RIL23RECE1 | |
| SCHEMBL30598170 | 0.92 | NPBWR1 (0.61) | RXFP1NPBWR1IL23R | |
| SCHEMBL30242111 | 0.91 | IL23R (0.59) | RXFP1NPBWR1IL23RPCSK9PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111713-A9 | POLYPEPTIDE CONTAINING DISULFIDE BONDS AND CAPABLE OF INHIBITING ACTIVITY OF SERINE PROTEASE, DERIVED HYBRID PEPTIDE THEREOF, AND USE THEREOF | 中国医学科学院药物研究所 | 2023-07-27 | — | — | WO | disclosed |