SCHEMBL30637763

SCHEMBL30637763

CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 5/20 0.61
▸ NPBWR1 P48145 4/20 0.57
▸ GLP1R P43220 5/20 0.56
▸ ECE1 P42892 1/20 0.56
▸ MUS81 Q96NY9 1/20 0.56
▸ GRPR P30550 3/20 0.54
▸ IL23R Q5VWK5 1/20 0.53
▸ PTH1R Q03431 1/20 0.53
▸ OPRD1 P41143 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30578571 0.98 RXFP1 (0.58) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL31453816 0.97 RXFP1 (0.65) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL30874393 0.96 RXFP1 (0.60) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL30874386 0.94 RXFP1 (0.58) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL30598172 0.93 RXFP1 (0.63) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL30076208 0.93 GLP1R (0.63) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL3113818 0.92 RXFP1 (0.54) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL29370686 0.91 NPBWR1 (0.56) RXFP1NPBWR1GRPRIL23RPTH1R
SCHEMBL29373303 0.91 GLP1R (0.65) RXFP1NPBWR1GLP1RECE1MUS81
SCHEMBL30627035 0.90 RXFP1 (0.66) RXFP1NPBWR1GLP1RECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US claimed
CN-117098843-A Subtilisin variants and uses thereof 费森尤斯卡比有限公司 2023-11-21 — — CN claimed
WO-2025264809-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US disclosed
CN-111819191-B Chemoenzymatic synthesis of liraglutide, soxhlet Ma Lutai and GLP-1 费森尤斯卡比有限公司 2024-08-20 — — CN disclosed
US-20240247042-A1 GLUCAGON LIKE PEPTIDE COMPOUNDS NOVARTIS AG (CH) 2024-07-25 — — US disclosed
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES Nanjing Finepeptide Biopharmaceutical Co.,Ltd (CN) 2024-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES GLP1R, IAPP, GCG RXFP1 271/4885NPBWR1 431/4885GLP1R 1/4885
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG RXFP1 83/4885NPBWR1 188/4885GLP1R 1/4885
US-20240247042-A1 GLUCAGON LIKE PEPTIDE COMPOUNDS GLP1R, IAPP, GPR119 RXFP1 93/4885NPBWR1 198/4885GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback