SCHEMBL30874406

SCHEMBL30874406

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(N)=O)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPBWR1 P48145 12/20 0.57
KISS1R Q969F8 3/20 0.55
IL23R Q5VWK5 2/20 0.54
OPRD1 P41143 1/20 0.53
GRPR P30550 1/20 0.52
RXFP1 Q9HBX9 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL677586 0.95 NPBWR1 (0.56) NPBWR1KISS1RIL23ROPRD1RXFP1
SCHEMBL29375423 0.95 NPBWR1 (0.56) NPBWR1KISS1RIL23ROPRD1RXFP1
SCHEMBL30874395 0.94 NPBWR1 (0.56) NPBWR1KISS1RIL23ROPRD1GRPR
SCHEMBL31614451 0.93 NPBWR1 (0.63) NPBWR1IL23RRXFP1
SCHEMBL30253514 0.92 NPBWR1 (0.60) NPBWR1IL23RRXFP1
SCHEMBL30198266 0.92 NPBWR1 (0.60) NPBWR1IL23RRXFP1
SCHEMBL31294865 0.91 NPBWR1 (0.61) NPBWR1IL23RRXFP1
SCHEMBL2194373 0.90 KISS1R (0.57) NPBWR1KISS1RIL23R
SCHEMBL30874400 0.89 RXFP1 (0.62) NPBWR1KISS1ROPRD1RXFP1
SCHEMBL31743243 0.89 KISS1R (0.58) NPBWR1KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES Nanjing Finepeptide Biopharmaceutical Co.,Ltd (CN) 2024-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES GLP1R, IAPP, GCG NPBWR1 431/4885KISS1R 1181/4885IL23R 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.