⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770032 | 1.00 | — | — | |
| SCHEMBL30657568 | 0.81 | — | — | |
| SCHEMBL724866 | 0.79 | CHRNA7 (0.74) | — | |
| SCHEMBL29485692 | 0.79 | CHRNA7 (0.74) | — | |
| SCHEMBL727185 | 0.79 | CYP1A2 (0.62) | — | |
| Nicotinyl Alcohol SCHEMBL16986785 | 0.76 | KDM4E (0.65) | — | |
| SCHEMBL45429 | 0.75 | — | — | |
| SCHEMBL8219678 | 0.75 | — | — | |
| SCHEMBL317315 | 0.75 | — | — | |
| SCHEMBL6138365 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092040-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2025-03-20 | — | — | US | disclosed |
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
| US-11999730-B1 | AKT1 modulators | ALTEROME THERAPEUTICS, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240174667-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-05-30 | — | — | US | disclosed |