Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13172238 | 1.00 | BACE1 (0.38) | BACE1KDM1AKDM1BDGAT1CTSD | |
| SCHEMBL16905433 | 0.81 | KDM1A (0.39) | BACE1KDM1ABACE2CMA1AHR | |
| SCHEMBL257533 | 0.79 | BACE1 (0.49) | BACE1 | |
| SCHEMBL24665777 | 0.78 | CYP3A4 (0.38) | BACE1THRBPDE2A | |
| SCHEMBL14625577 | 0.76 | PTGDR (0.37) | BACE1KDM1A | |
| SCHEMBL29581168 | 0.76 | KDM1A (0.42) | BACE1KDM1AKDM1BDGAT1CTSD | |
| SCHEMBL30680681 | 0.76 | DGAT1 (0.40) | BACE1KDM1AKDM1BDGAT1CMA1 | |
| SCHEMBL12982682 | 0.76 | DGAT1 (0.40) | BACE1KDM1AKDM1BDGAT1CMA1 | |
| SCHEMBL2147689 | 0.76 | KDM1A (0.42) | BACE1KDM1AKDM1BDGAT1CTSD | |
| SCHEMBL5176991 | 0.76 | CMA1 (0.35) | KDM1ACMA1AHRPNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |