Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924296 | 0.91 | PTGDR (0.47) | PTGDRPTGDR2SLC6A4SLC6A3 | |
| SCHEMBL24685578 | 0.88 | HTR2C (0.41) | PTGDRPTGDR2SLC6A4SRD5A1HTR2A | |
| SCHEMBL30680720 | 0.85 | BACE1 (0.35) | PTGDRPTGDR2SLC6A4SLC6A3MAP3K14 | |
| SCHEMBL30680705 | 0.81 | POLB (0.32) | SLC6A4SLC6A3MAP3K14SRD5A1BACE1 | |
| SCHEMBL257533 | 0.79 | BACE1 (0.49) | SRD5A1BACE1HDAC6 | |
| SCHEMBL9921757 | 0.79 | SLC6A3 (0.49) | PTGDRPTGDR2SLC6A4SLC6A3MAP3K14 | |
| SCHEMBL29924946 | 0.78 | ICMT (0.38) | SLC6A4SLC6A3MAP3K14SRD5A1HTR2A | |
| SCHEMBL24665777 | 0.78 | CYP3A4 (0.38) | BACE1 | |
| SCHEMBL24186494 | 0.77 | BACE1 (0.39) | HTR2AHTR2CBACE1HDAC6 | |
| SCHEMBL30874809 | 0.76 | BACE1 (0.38) | BACE1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006546-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-01-18 | — | — | WO | disclosed |