Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874815 | 0.78 | DPP4 (0.45) | DPP4GAAHTR1AHTR7PDK2 | |
| SCHEMBL30874913 | 0.76 | DPP4 (0.43) | DPP4GAAHTR1AHTR7SCN9A | |
| SCHEMBL30874932 | 0.75 | DPP4 (0.45) | DPP4GAAHTR1AHTR7PDK2 | |
| SCHEMBL30874931 | 0.71 | DPP4 (0.51) | DPP4HTR1AHTR7SCN9APDK2 | |
| SCHEMBL30874926 | 0.71 | DPP4 (0.44) | DPP4GAAHTR1AHTR7 | |
| SCHEMBL30874850 | 0.71 | DPP4 (0.47) | DPP4GAAHTR1AHTR7CFD | |
| SCHEMBL30975227 | 0.70 | DPP4 (0.48) | DPP4HTR1AHTR7 | |
| SCHEMBL15856041 | 0.69 | DPP4 (0.44) | DPP4HTR1AHTR7 | |
| SCHEMBL30874954 | 0.69 | KMT2A (0.45) | DPP4HTR1AHTR7CFD | |
| SCHEMBL30874923 | 0.68 | DPP4 (0.44) | DPP4HTR1AHTR7CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |