Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3181242 | 0.83 | ACE (0.41) | ACE | |
| SCHEMBL17188728 | 0.83 | DPP4 (0.44) | DPP4ACE | |
| SCHEMBL3181235 | 0.83 | ACE (0.41) | ACE | |
| SCHEMBL18779110 | 0.83 | DPP4 (0.44) | DPP4ACE | |
| SCHEMBL1493753 | 0.79 | DPP4 (0.47) | DPP4HTR1AHTR7ACE | |
| SCHEMBL8772871 | 0.79 | DPP4 (0.56) | DPP4HTR1AHTR7ACE | |
| SCHEMBL8772866 | 0.79 | DPP4 (0.56) | DPP4HTR1AHTR7ACE | |
| Bromide SCHEMBL9464396 | 0.77 | DPP4 (0.54) | DPP4HTR1AHTR7ACE | |
| Hydrochloric Acid SCHEMBL19692659 | 0.77 | DPP4 (0.54) | DPP4HTR1AHTR7ACE | |
| SCHEMBL16393157 | 0.77 | DPP4 (0.42) | DPP4HTR1AHTR7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131265-A1 | COMPOUND FOR TREATING PI3Kγ-MEDIATED DISEASES AND USE THEREOF | 中国科学院合肥物质科学研究院 | 2024-06-27 | — | — | WO | disclosed |