Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.51 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874932 | 0.80 | DPP4 (0.45) | DPP4CFDSPHK2SPHK1HTR1A | |
| SCHEMBL30874850 | 0.78 | DPP4 (0.47) | DPP4CFDHTR1AHTR7 | |
| SCHEMBL30874815 | 0.75 | DPP4 (0.45) | DPP4CFDSPHK2SPHK1HTR1A | |
| SCHEMBL30874829 | 0.74 | GFER (0.45) | DPP4CFDHTR1AHTR7 | |
| SCHEMBL30874923 | 0.73 | DPP4 (0.44) | DPP4CFDHTR1AHTR7 | |
| SCHEMBL12986210 | 0.73 | PDK2 (0.45) | PDK2 | |
| SCHEMBL31710554 | 0.71 | DPP4 (0.59) | DPP4SPHK2SPHK1SCN9AFPR2 | |
| SCHEMBL30874822 | 0.71 | DPP4 (0.43) | DPP4CFDSPHK2SPHK1HTR1A | |
| SCHEMBL30874913 | 0.71 | DPP4 (0.43) | DPP4SPHK2SPHK1HTR1AHTR7 | |
| SCHEMBL30874905 | 0.71 | DPP4 (0.40) | DPP4CFDHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |