Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | HTR7 | P34969 | 6/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874814 | 0.74 | OPRM1 (0.41) | DPP4OPRM1OPRL1HTR1AHTR7 | |
| SCHEMBL1483515 | 0.74 | TSHR (0.55) | OPRM1OPRL1TSHR | |
| SCHEMBL13812370 | 0.73 | GAA (0.43) | — | |
| SCHEMBL28466485 | 0.72 | GAA (0.45) | TSHR | |
| SCHEMBL30455271 | 0.71 | DDB1 (0.40) | — | |
| SCHEMBL15856041 | 0.71 | DPP4 (0.44) | DPP4HTR1AHTR7ACE | |
| SCHEMBL8772871 | 0.69 | DPP4 (0.56) | DPP4HTR1AHTR7ACE | |
| SCHEMBL1493753 | 0.69 | DPP4 (0.47) | DPP4HTR1AHTR7ACE | |
| SCHEMBL8772866 | 0.69 | DPP4 (0.56) | DPP4HTR1AHTR7ACE | |
| SCHEMBL3833137 | 0.69 | TSHR (0.44) | ACETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |