Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.56 |
| ▸ | PREP | P48147 | 1/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772866 | 1.00 | DPP4 (0.56) | DPP4PREPFAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL29548868 | 0.98 | DPP4 (0.54) | DPP4PREPFAPDPP8DPP9 | |
| Bromide SCHEMBL9464510 | 0.98 | DPP4 (0.54) | DPP4PREPFAPDPP8DPP9 | |
| Bromide SCHEMBL9464396 | 0.98 | DPP4 (0.54) | DPP4PREPFAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL19692659 | 0.98 | DPP4 (0.54) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL10884099 | 0.85 | DPP4 (0.54) | DPP4ACEHTR1AHTR7 | |
| SCHEMBL1493753 | 0.85 | DPP4 (0.47) | DPP4ACEHTR1AHTR7 | |
| Glycyl Proline SCHEMBL155067 | 0.85 | ACE (0.62) | DPP4PREPFAPDPP8DPP9 | |
| Glycyl Proline SCHEMBL30051559 | 0.85 | ACE (0.62) | DPP4PREPFAPDPP8DPP9 | |
| Glycyl Proline SCHEMBL155066 | 0.85 | ACE (0.62) | DPP4PREPFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599791-A | BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | GRUPPO LEPETIT SPA (IT) | 1997-02-04 | — | — | US | claimed |
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | claimed |
| EP-0565567-B1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | LEPETIT SPA (IT) | 1995-01-18 | — | — | EP | claimed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | claimed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | claimed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | claimed |
| US-20240409531-A1 | BENZOXAZINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | MERCK SHARP & DOHME LLC (US) | 2024-12-12 | — | — | US | disclosed |
| US-11858924-B2 | N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-quinoline-4-carboxamides | ASTRAZENECA (SE) | 2024-01-02 | — | — | US | disclosed |
| US-20230312550-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES | ASTRAZENECA AB (SE) | 2023-10-05 | — | — | US | disclosed |
| EP-2323981-B1 | PROCESS FOR THE PREPARATION OF A MACROCYCLE | HOFFMANN LA ROCHE (CH) | 2014-03-12 | — | — | EP | disclosed |
| WO-2009142842-A9 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2009142842-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| EP-0800510-A1 | HYDROXAMIC ACID-CONTAINING INHIBITORS OF MATRIX METALLOPROTEASES | THE PROCTER & GAMBLE COMPANY (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020918-A1 | HYDROXAMIC ACID-CONTAINING INHIBITORS OF MATRIX METALLOPROTEASES | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-11 | — | — | WO | disclosed |
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | disclosed |
| EP-0565567-B1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | LEPETIT SPA (IT) | 1995-01-18 | — | — | EP | disclosed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |
| US-4558034-A | Inhibitors of bacterial collagenase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) | 1985-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409531-A1 | BENZOXAZINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | NFATC1, ACIN1, GZMB | DPP4 3450/4885PREP 925/4885FAP 4628/4885 |
| US-20230312550-A1 | N-(2-(4-CYANOTHIAZOLIDIN-3-YL)-2-OXOETHYL)-QUINOLINE-4-CARBOXAMIDES | FAP, PREP, CTRL | DPP4 39/4885PREP 2/4885FAP 1/4885 |
| US-11858924-B2 | N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-quinoline-4-carboxamides | FAP, PREP, CTRL | DPP4 39/4885PREP 2/4885FAP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.