Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 4/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874867 | 0.80 | DPP4 (0.42) | DPP4ACESPHK2SPHK1HTR1A | |
| SCHEMBL2177077 | 0.79 | DPP4 (0.57) | DPP4ACESPHK2SPHK1HTR1A | |
| SCHEMBL474918 | 0.79 | DPP4 (0.57) | DPP4ACESPHK2SPHK1HTR1A | |
| SCHEMBL30874856 | 0.78 | DPP4 (0.39) | DPP4HTR1AHTR7DHFR | |
| SCHEMBL30874862 | 0.76 | CYP19A1 (0.47) | DPP4ACEHTR1AHTR7DHFR | |
| SCHEMBL30874919 | 0.74 | DPP4 (0.45) | DPP4ACEHTR1AHTR7 | |
| SCHEMBL30874864 | 0.74 | VNN1 (0.47) | DPP4ACEHTR1AHTR7DHFR | |
| SCHEMBL30874874 | 0.73 | VNN1 (0.44) | DPP4ACESPHK2HTR1AHTR7 | |
| SCHEMBL19961337 | 0.72 | TRPV6 (0.46) | SMN1; SMN2 | |
| SCHEMBL30874798 | 0.72 | VNN1 (0.62) | DPP4ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |