Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 6/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | HTR7 | P34969 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874905 | 0.81 | DPP4 (0.40) | DPP4CFDHTR1AHTR7VNN1 | |
| SCHEMBL30874954 | 0.78 | KMT2A (0.45) | DPP4CFDHTR1AHTR7KMT2A | |
| SCHEMBL30874949 | 0.76 | ALDH1A1 (0.44) | DPP4HTR1AHTR7VNN1 | |
| SCHEMBL30874951 | 0.74 | DPP4 (0.43) | DPP4HTR1AHTR7ACE | |
| SCHEMBL30874931 | 0.74 | DPP4 (0.51) | DPP4CFDHTR1AHTR7 | |
| SCHEMBL15856041 | 0.73 | DPP4 (0.44) | DPP4HTR1AHTR7ACE | |
| SCHEMBL30874923 | 0.73 | DPP4 (0.44) | DPP4CFDHTR1AHTR7 | |
| SCHEMBL30874846 | 0.73 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL4182356 | 0.73 | DPP4 (0.47) | DPP4HTR1AHTR7ACE | |
| SCHEMBL6471923 | 0.73 | DPP4 (0.47) | DPP4HTR1AHTR7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |