Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874812 | 0.86 | DPP4 (0.47) | DPP4DPP9HTR1AHTR7NPC1 | |
| SCHEMBL30874836 | 0.81 | CNR2 (0.37) | DPP4DPP9PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30874935 | 0.77 | DPP4 (0.41) | DPP4DPP9HTR1AHTR7PIK3CD | |
| SCHEMBL30874948 | 0.71 | DPP4 (0.44) | DPP4DPP9HTR1AHTR7NPC1 | |
| SCHEMBL26841880 | 0.71 | TACR1 (0.41) | — | |
| SCHEMBL30874932 | 0.71 | DPP4 (0.45) | DPP4SPHK2SPHK1HTR1AHTR7 | |
| SCHEMBL30874850 | 0.71 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL30874847 | 0.70 | DPP4 (0.47) | DPP4DPP9HTR1AHTR7NPC1 | |
| SCHEMBL30874915 | 0.70 | DPP4 (0.45) | DPP4DPP9HTR1AHTR7 | |
| SCHEMBL30975227 | 0.69 | DPP4 (0.48) | DPP4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |