Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874847 | 0.81 | DPP4 (0.47) | DPP4DPP9NPC1RAB9AHTR1A | |
| SCHEMBL30874812 | 0.80 | DPP4 (0.47) | DPP4CCNE1CDK2DPP9CNR2 | |
| SCHEMBL30874935 | 0.79 | DPP4 (0.41) | DPP4DPP9CNR2VNN1HTR1A | |
| SCHEMBL30874917 | 0.78 | CNR2 (0.41) | DPP4CCNE1CDK2GSK3BCNR2 | |
| SCHEMBL30874876 | 0.77 | DPP4 (0.39) | DPP4DPP9PREPHTR1AHTR7 | |
| SCHEMBL13570435 | 0.74 | VHL (0.52) | DPP4CCNE1CDK2GSK3BDPP9 | |
| SCHEMBL21696738 | 0.74 | VHL (0.52) | DPP4CCNE1CDK2GSK3BDPP9 | |
| SCHEMBL30874864 | 0.74 | VNN1 (0.47) | DPP4DPP9VNN1HTR1AHTR7 | |
| SCHEMBL30874909 | 0.73 | VNN1 (0.47) | DPP4DPP9CNR2VNN1HTR1A | |
| SCHEMBL30874955 | 0.73 | DPP4 (0.42) | DPP4DPP9VNN1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |