Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 8/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554505 | 0.83 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL30874951 | 0.83 | DPP4 (0.43) | DPP4HTR1AHTR7 | |
| SCHEMBL21696498 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP2B6 | |
| SCHEMBL21696700 | 0.77 | F2 (0.43) | — | |
| SCHEMBL30874905 | 0.76 | DPP4 (0.40) | DPP4VNN1HTR1AHTR7 | |
| SCHEMBL30874829 | 0.76 | GFER (0.45) | DPP4VNN1HTR1AHTR7 | |
| SCHEMBL15126455 | 0.74 | POLB (0.52) | ALDH1A1 | |
| SCHEMBL15856041 | 0.73 | DPP4 (0.44) | DPP4HTR1AHTR7 | |
| SCHEMBL30874954 | 0.73 | KMT2A (0.45) | ALDH1A1DPP4HTR1AHTR7 | |
| SCHEMBL30874862 | 0.71 | CYP19A1 (0.47) | DPP4CYP19A1VNN1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |