Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874811 | 0.79 | CFD (0.40) | DPP4DPP8DPP7CFD | |
| SCHEMBL30874846 | 0.77 | DPP4 (0.47) | DPP4DPP9HTR1AHTR7 | |
| SCHEMBL30874926 | 0.74 | DPP4 (0.44) | DPP4GAADPP9HTR1AHTR7 | |
| SCHEMBL30874876 | 0.73 | DPP4 (0.39) | DPP4DPP9HTR1AHTR7 | |
| SCHEMBL30874847 | 0.72 | DPP4 (0.47) | DPP4DPP8DPP7DPP9HTR1A | |
| SCHEMBL30874923 | 0.72 | DPP4 (0.44) | DPP4CFDDPP9HTR1AHTR7 | |
| SCHEMBL30874951 | 0.71 | DPP4 (0.43) | DPP4HTR1AHTR7 | |
| SCHEMBL15856041 | 0.70 | DPP4 (0.44) | DPP4HTR1AHTR7 | |
| SCHEMBL30874948 | 0.69 | DPP4 (0.44) | DPP4DPP9HTR1AHTR7KMT2A | |
| SCHEMBL6471923 | 0.69 | DPP4 (0.47) | DPP4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956985-A | Inhibitors of glycogen synthase 1 (GYS 1) and methods of use thereof | 梅兹治疗公司 | 2024-04-30 | — | — | CN | disclosed |