Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.47 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.47 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782031 | 0.77 | SYK (0.49) | PDE3BPDE3AMETKDRBMPR1B | |
| SCHEMBL21225651 | 0.75 | MAPT (0.50) | MAPK10MAPK1CBFB | |
| SCHEMBL782867 | 0.74 | SYK (0.44) | PDE3BPDE3AMETKDRBMPR1B | |
| SCHEMBL24291075 | 0.74 | FGFR2 (0.43) | PDE3BPDE3AMAPK10FGFR2FGFR3 | |
| Hydrochloric Acid SCHEMBL16161694 | 0.74 | SYK (0.44) | PDE3BPDE3AMETKDRBMPR1B | |
| SCHEMBL29400331 | 0.72 | TLR9 (0.63) | KDRACVR1CHEK1FGFR1FGFR2 | |
| SCHEMBL27090893 | 0.72 | MAPK1 (0.52) | KDRACVR1FGFR1FGFR2FGFR4 | |
| SCHEMBL29590529 | 0.72 | MAPK1 (0.52) | KDRACVR1FGFR1FGFR2FGFR4 | |
| SCHEMBL30646549 | 0.72 | MAPK1 (0.52) | KDRMAPK10FGFR1FGFR2FGFR4 | |
| SCHEMBL29071545 | 0.71 | CHEK1 (0.53) | PDE3BPDE3AMETKDRBMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050428-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050428-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | GSPT1, GGT1, VHL | PDE3B 1951/4885PDE3A 1923/4885MET 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.