Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13164125 | 1.00 | LOXL2 (0.44) | LOXL2PNMTF2TAAR1HRH3 | |
| SCHEMBL3694809 | 0.83 | LOXL2 (0.41) | LOXL2PNMTF2TAAR1HRH3 | |
| SCHEMBL22894079 | 0.82 | PDE2A (0.41) | LOXL2PNMTF2TAAR1HRH3 | |
| SCHEMBL26700116 | 0.80 | LOXL2 (0.39) | LOXL2PNMTF2ABATENPP2 | |
| SCHEMBL29467938 | 0.80 | LOXL2 (0.39) | LOXL2PNMTF2ABATENPP2 | |
| SCHEMBL29468007 | 0.79 | LOXL2 (0.38) | LOXL2PNMTF2TAAR1HRH3 | |
| SCHEMBL28711316 | 0.79 | LOXL2 (0.38) | LOXL2PNMTF2TAAR1HRH3 | |
| SCHEMBL28711317 | 0.79 | LOXL2 (0.38) | LOXL2PNMTF2TAAR1HRH3 | |
| SCHEMBL8191012 | 0.78 | GRIN2B (0.41) | TAAR1CYP2A6KCNH2 | |
| SCHEMBL110823 | 0.77 | LOXL2 (0.52) | LOXL2PNMTTAAR1HRH3ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |