SCHEMBL30876263

SCHEMBL30876263

O=S(=O)(Cl)c1cc(F)c(F)c(Br)c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 18/20 0.46
CA2 P00918 18/20 0.46
CA9 Q16790 13/20 0.46
CA12 O43570 4/20 0.39
CA7 P43166 4/20 0.39
CA13 Q8N1Q1 1/20 0.39
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA14 Q9ULX7 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
EPAS1 Q99814 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16177831 1.00 CA1 (0.46) CA1CA2CA9CA12CA7
SCHEMBL282282 0.84 CA1 (0.41) CA1CA2CA9CA12CA7
SCHEMBL31487920 0.81 CA2 (0.68) CA1CA2CA9CA12CA7
SCHEMBL1541882 0.80 CA1 (0.41) CA1CA2CA9CA12CA7
SCHEMBL19748545 0.80 CA1 (0.43) CA1CA2CA9CA12CA7
SCHEMBL23242993 0.76 CA2 (0.43) CA1CA2CA9CA12CA7
SCHEMBL31267023 0.76 CA1 (0.39) CA1CA2CA9CA12CA7
SCHEMBL20940087 0.76 CA1 (0.40) CA1CA2CA9CA12CA7
SCHEMBL19747741 0.76 CA1 (0.40) CA1CA2CA9CA12CA7
SCHEMBL121437 0.75 CA2 (0.42) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462555-A Sulfonamide compound and application thereof 上海科技大学 2025-02-18 CN disclosed
WO-2025031360-A1 SULFONAMIDE COMPOUND AND USE THEREOF 上海科技大学 2025-02-13 WO disclosed
CN-118005606-A TEAD inhibitors 武汉人福创新药物研发中心有限公司 2024-05-10 CN disclosed