Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 13/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30876283 | 0.89 | KAT8 (0.41) | KAT8KAT6AACLYMEN1KMT2A | |
| SCHEMBL30876250 | 0.86 | KAT8 (0.39) | KAT8KAT6AACLYMEN1KMT2A | |
| SCHEMBL30876235 | 0.80 | KAT8 (0.33) | KAT8KAT6AKCNH2 | |
| SCHEMBL30876248 | 0.78 | MEN1 (0.37) | ACLYMEN1KMT2ATNFNOD2 | |
| SCHEMBL30876257 | 0.77 | KAT8 (0.40) | KAT8KAT6AACLYMEN1KMT2A | |
| SCHEMBL29438856 | 0.68 | MEN1 (0.49) | KAT8ACLYMEN1KMT2A | |
| SCHEMBL30876268 | 0.68 | BRD4 (0.43) | KAT8 | |
| SCHEMBL30876249 | 0.67 | L3MBTL1 (0.37) | ACLYMEN1KMT2ATNFNOD2 | |
| SCHEMBL30129825 | 0.67 | KAT8 (0.38) | KAT8KAT6AACLYMEN1KMT2A | |
| SCHEMBL30876296 | 0.67 | KCNH2 (0.34) | KAT8KAT6ANTRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |