Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30876249 | 0.88 | L3MBTL1 (0.37) | MEN1KMT2APOLBL3MBTL1MMP2 | |
| SCHEMBL30876233 | 0.84 | L3MBTL1 (0.36) | MEN1KMT2APOLBL3MBTL1MMP2 | |
| SCHEMBL30876250 | 0.84 | KAT8 (0.39) | MEN1KMT2AL3MBTL1TNFNOD2 | |
| SCHEMBL30876219 | 0.80 | L3MBTL1 (0.37) | MEN1KMT2APOLBL3MBTL1MMP2 | |
| SCHEMBL30876273 | 0.78 | KAT8 (0.40) | MEN1KMT2ATNFNOD2NOD1 | |
| SCHEMBL30135124 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2APOLBL3MBTL1MMP2 | |
| SCHEMBL30876228 | 0.77 | BMP1 (0.47) | L3MBTL1MMP9MMP13ALDH1A1CYP1A2 | |
| SCHEMBL29206993 | 0.77 | BMP1 (0.47) | L3MBTL1MMP9MMP13ALDH1A1CYP1A2 | |
| SCHEMBL30876275 | 0.74 | NAMPT (0.46) | MEN1KMT2AMMP9MMP13BMP1 | |
| SCHEMBL29206926 | 0.74 | NAMPT (0.46) | MEN1KMT2AMMP9MMP13BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |