SCHEMBL30876366

SCHEMBL30876366

COC(=O)COc1ccc(N)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 2/20 0.53
HSD17B10 Q99714 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.50
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
HPGD P15428 3/20 0.48
MAPT P10636 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
NPC1 O15118 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PTGS2 P35354 2/20 0.47
CBX7 O95931 1/20 0.46
MCL1 Q07820 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19317367 1.00 ALDH1A1 (0.53) ALDH1A1KDM4EHSD17B10SMN1; SMN2ATM
SCHEMBL23121220 0.87 ALDH1A1 (0.53) ALDH1A1KDM4EHSD17B10SMN1; SMN2ATM
SCHEMBL29991893 0.87 ALDH1A1 (0.53) ALDH1A1KDM4EHSD17B10SMN1; SMN2ATM
SCHEMBL7447346 0.86 GAA (0.56) ALDH1A1KDM4EHSD17B10SMN1; SMN2ATM
SCHEMBL584257 0.85 ATM (0.65) ALDH1A1KDM4EHSD17B10ATML3MBTL1
Hydrochloric Acid SCHEMBL8323913 0.84 GAA (0.55) ALDH1A1KDM4EHSD17B10SMN1; SMN2ATM
SCHEMBL7344872 0.83 MCL1 (0.49) ALDH1A1KDM4EHSD17B10SMN1; SMN2ATM
SCHEMBL6838793 0.83 MCL1 (0.66) ALDH1A1KDM4EHSD17B10SMN1; SMN2L3MBTL1
SCHEMBL8770592 0.83 MAPT (0.55) ALDH1A1KDM4EHSD17B10ATML3MBTL1
SCHEMBL1731148 0.83 ATM (0.46) SMN1; SMN2ATML3MBTL1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 WO disclosed
EP-3426246-B1 THIAZOLIDINONE COMPOUNDS AND USE THEREOF NATIONAL HEALTH RES INST (TW) 2024-05-01 EP disclosed