Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20685285 | 0.88 | MAPT (0.57) | MAPTATMMEN1KMT2ATP53 | |
| SCHEMBL19317367 | 0.83 | ALDH1A1 (0.53) | MAPTATMMEN1KMT2AL3MBTL1 | |
| SCHEMBL30876366 | 0.83 | ALDH1A1 (0.53) | MAPTATMMEN1KMT2AL3MBTL1 | |
| SCHEMBL7447346 | 0.82 | GAA (0.56) | MAPTATMTP53L3MBTL1TDP1 | |
| SCHEMBL6141297 | 0.81 | ATM (0.40) | MAPTATMMEN1PKMKMT2A | |
| Hydrochloric Acid SCHEMBL8323913 | 0.81 | GAA (0.55) | MAPTATMTP53L3MBTL1TDP1 | |
| SCHEMBL8770574 | 0.80 | MAPT (0.67) | MAPTKMT2ATP53RXFP1L3MBTL1 | |
| SCHEMBL6838793 | 0.80 | MCL1 (0.66) | MAPTMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL7344872 | 0.80 | MCL1 (0.49) | MAPTATMMEN1PKMKMT2A | |
| SCHEMBL1731148 | 0.79 | ATM (0.46) | MAPTATML3MBTL1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |