Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781008 | 1.00 | POLB (0.55) | POLBSMN1; SMN2RAB9ANPC1IDO1 | |
| SCHEMBL9006468 | 0.82 | ALOX5 (0.50) | POLBNPC1IDO1CYP1A2CYP3A4 | |
| SCHEMBL10263771 | 0.82 | POLB (0.69) | POLBSMN1; SMN2RAB9ANPC1IDO1 | |
| SCHEMBL29715410 | 0.79 | POLB (0.55) | POLBSMN1; SMN2RAB9ANPC1IDO1 | |
| SCHEMBL29715308 | 0.79 | POLB (0.55) | POLBSMN1; SMN2RAB9ANPC1CYP3A4 | |
| SCHEMBL23092860 | 0.79 | POLB (0.55) | POLBSMN1; SMN2RAB9ANPC1IDO1 | |
| SCHEMBL29715299 | 0.79 | POLB (0.55) | POLBSMN1; SMN2RAB9ANPC1IDO1 | |
| SCHEMBL23092362 | 0.79 | POLB (0.55) | POLBSMN1; SMN2RAB9ANPC1IDO1 | |
| SCHEMBL23092549 | 0.79 | POLB (0.55) | POLBSMN1; SMN2RAB9ANPC1CYP3A4 | |
| SCHEMBL11419059 | 0.79 | POLB (0.69) | POLBSMN1; SMN2RAB9ANPC1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836270-A | USP30 inhibitors and uses thereof | 文森雷生物科学股份有限公司 | 2024-04-05 | — | — | CN | disclosed |