SCHEMBL9006468

SCHEMBL9006468

Oc1ccc(SCc2ccccc2)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
POLB P06746 1/20 0.48
DAO P14920 2/20 0.44
GFER P55789 2/20 0.44
GAA P10253 1/20 0.44
PTPRC P08575 1/20 0.42
NPC1 O15118 2/20 0.42
CA2 P00918 2/20 0.41
CA4 P22748 2/20 0.41
GALK1 P51570 1/20 0.41
IDO1 P14902 1/20 0.41
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006548 0.82 MEN1 (0.53) DAONPC1IDO1MEN1KMT2A
SCHEMBL8781008 0.82 POLB (0.55) POLBDAOPTPRCNPC1CA2
SCHEMBL9006810 0.82 DAO (0.47) POLBDAOGFERGAACA2
SCHEMBL30876802 0.82 POLB (0.55) POLBDAOPTPRCNPC1CA2
SCHEMBL77392 0.80 POLB (0.61) POLBDAOPTPRCCA2CA4
SCHEMBL9006523 0.78 MEN1 (0.51) DAONPC1IDO1MEN1KMT2A
SCHEMBL8781039 0.76 ALDH1A1 (0.64) POLBGAAMEN1KMT2ACYP1A2
SCHEMBL8156398 0.76 CA2 (0.49) POLBDAOGAAPTPRCCA2
SCHEMBL30876805 0.76 ALDH1A1 (0.64) POLBGAAMEN1KMT2ACYP1A2
SCHEMBL9140935 0.76 TYR (0.44) ALOX5GFERGAACA2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623341-B1 Use of 4-thioresorcin derivatives in skin whitening cosmetic or dermopharmaceutical compositions OREAL (FR) 1996-10-16 EP claimed
US-5468472-A And containing humectant, surfactant, keratolytic agent, antiinflammatory agent, antioxidant, preservative, fragrance, sunscreen L'OREAL (FR) 1995-11-21 US claimed
JP-3268995-A None JP disclosed
US-5468472-A And containing humectant, surfactant, keratolytic agent, antiinflammatory agent, antioxidant, preservative, fragrance, sunscreen L'OREAL (FR) 1995-11-21 US disclosed
JP-H03268995-A THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1991-11-29 JP disclosed