SCHEMBL30876809

SCHEMBL30876809

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nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 13/20 0.52
BACE2 Q9Y5Z0 3/20 0.52
CTSD P07339 2/20 0.50
MME P08473 2/20 0.45
ENPEP Q07075 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31666009 0.96 BACE1 (0.50) BACE1BACE2CTSDMME
SCHEMBL30837136 0.94 BACE1 (0.53) BACE1BACE2CTSDENPEP
SCHEMBL29880484 0.93 BACE1 (0.48) BACE1BACE2CTSDMMEENPEP
SCHEMBL30814697 0.93 BACE1 (0.48) BACE1BACE2CTSDMME
SCHEMBL30099600 0.92 MME (0.56) BACE1BACE2CTSDMME
SCHEMBL29544149 0.92 MME (0.56) BACE1BACE2CTSDMME
SCHEMBL29873713 0.92 ENPEP (0.50) BACE1ENPEP
SCHEMBL29466705 0.91 BACE1 (0.47) BACE1BACE2CTSDMMEENPEP
SCHEMBL31307239 0.91 BACE1 (0.45) BACE1BACE2CTSDMME
SCHEMBL10439241 0.89 ALDH1A1 (0.47) BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025047993-A1 ANTI-DOPPEL ANTIBODY DRUG CONJUGATES PHAROSGEN CO., LTD. (KR) 2025-03-06 WO claimed
US-20240091372-A1 ANTI-DOPPEL ANTIBODY DRUG CONJUGATES SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-03-21 US claimed
US-20250302981-A1 NOVEL USE OF ANTICANCER AGENT PRODRUG CONJUGATE UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION (KR) 2025-10-02 US disclosed
WO-2025047993-A1 ANTI-DOPPEL ANTIBODY DRUG CONJUGATES PHAROSGEN CO., LTD. (KR) 2025-03-06 WO disclosed
US-20240091372-A1 ANTI-DOPPEL ANTIBODY DRUG CONJUGATES SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240091372-A1 ANTI-DOPPEL ANTIBODY DRUG CONJUGATES PHOSPHO1, CETP, CD79B BACE1 3889/4885BACE2 3569/4885CTSD 2828/4885
US-20250302981-A1 NOVEL USE OF ANTICANCER AGENT PRODRUG CONJUGATE KRAS, TP53, NRAS BACE1 4771/4885BACE2 4729/4885CTSD 4174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.