SCHEMBL3087696

SCHEMBL3087696

S=CN(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
ALDH1A1 P00352 4/20 0.33
ALOX15 P16050 2/20 0.33
MAPK1 P28482 2/20 0.33
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
KDM1A O60341 4/20 0.30
KCNH2 Q12809 2/20 0.30
MAOB P27338 2/20 0.30
RCOR1 Q9UKL0 2/20 0.30
GSK3B P49841 1/20 0.30
KDM1B Q8NB78 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11635074 0.74 CYP2A6 (0.42) CYP2A6ALDH1A1ALOX15MAPK1MAPT
SCHEMBL3091401 0.74 CYP2A6 (0.42) CYP2A6ALDH1A1ALOX15MAPK1MAPT
SCHEMBL3094976 0.74 LMNA (0.42) CYP2A6ALDH1A1ALOX15MAPTTDP1
SCHEMBL1741922 0.72 ALDH1A1 (0.39) ALDH1A1ALOX15MAPTTDP1
SCHEMBL23714869 0.67 CYP2A6 (0.57) CYP2A6ALDH1A1ALOX15MAPK1MAPT
SCHEMBL67004 0.67 CYP2A6 (0.57) CYP2A6ALDH1A1ALOX15MAPK1MAPT
Fluoride SCHEMBL31365993 0.65 CYP2A6 (0.53) CYP2A6ALDH1A1ALOX15MAPK1MAPT
SCHEMBL22502466 0.65 CYP2A6 (0.53) CYP2A6ALDH1A1ALOX15MAPK1MAPT
SCHEMBL18508 0.65
SCHEMBL3087692 0.63 CYP2A6 (0.42) CYP2A6ALDH1A1ALOX15MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100233415-A1 OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND MITSUI CHEMICALS, INC. (JP) 2010-09-16 US disclosed
EP-1997856-A1 OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND Mitsui Chemicals, Inc. (JP) 2008-12-03 EP disclosed