Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877399 | 0.91 | RAPGEF4 (0.43) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877468 | 0.89 | RAPGEF4 (0.44) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877392 | 0.84 | RAPGEF4 (0.48) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877349 | 0.81 | ALDH1A1 (0.38) | CA1CA2L3MBTL1HTTPOLB | |
| SCHEMBL30877498 | 0.81 | RAPGEF4 (0.43) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877504 | 0.81 | RAPGEF4 (0.43) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877309 | 0.81 | RAPGEF4 (0.45) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877321 | 0.79 | RAPGEF4 (0.43) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877275 | 0.78 | RAPGEF4 (0.45) | RAPGEF4CA1CA2L3MBTL1HTT | |
| SCHEMBL30877318 | 0.77 | RAPGEF4 (0.44) | RAPGEF4CA1CA2L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |