Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797067 | 0.77 | MCL1 (0.36) | DAOHDAC8HDAC6 | |
| SCHEMBL27283649 | 0.73 | — | — | |
| SCHEMBL8026005 | 0.69 | RARB (0.46) | L3MBTL1HTT | |
| SCHEMBL11185622 | 0.68 | — | — | |
| SCHEMBL12391039 | 0.67 | ASIC3 (0.50) | L3MBTL1ASIC3HAO1MAP3K14HTT | |
| SCHEMBL487465 | 0.67 | MAPT (0.56) | L3MBTL1ASIC3HAO1HTT | |
| Dimethylamine SCHEMBL700542 | 0.67 | MAPT (0.51) | L3MBTL1ASIC3HAO1HTT | |
| SCHEMBL1797065 | 0.66 | MCL1 (0.36) | DAOHDAC8HDAC6 | |
| Pivalate SCHEMBL27342904 | 0.66 | MCL1 (0.39) | — | |
| SCHEMBL5820056 | 0.65 | APP (0.55) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |