Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10125216 | 0.87 | POLB (0.45) | CYP2C9L3MBTL1GAANPSR1TSHR | |
| SCHEMBL17973534 | 0.85 | CYP2C9 (0.42) | CYP2C9L3MBTL1GAANPSR1TSHR | |
| SCHEMBL12393140 | 0.84 | KDM4E (0.46) | CYP2C9L3MBTL1TSHRTCF4CTNNB1 | |
| SCHEMBL3360534 | 0.84 | CYP2C9 (0.41) | CYP2C9L3MBTL1GAATSHRTCF4 | |
| SCHEMBL2184458 | 0.84 | CA1 (0.43) | CYP2C9L3MBTL1GAATSHRTCF4 | |
| SCHEMBL19564940 | 0.82 | POLB (0.41) | CYP2C9L3MBTL1TSHRTCF4CTNNB1 | |
| SCHEMBL10124994 | 0.82 | CYP2C9 (0.41) | CYP2C9L3MBTL1TSHRTCF4CTNNB1 | |
| SCHEMBL20816037 | 0.81 | PTGS2 (0.42) | KDM4EMEN1KMT2AMAPTPTGS2 | |
| SCHEMBL17971152 | 0.81 | CYP2C9 (0.39) | CYP2C9L3MBTL1TSHRTCF4CTNNB1 | |
| SCHEMBL18281394 | 0.80 | LMNA (0.43) | CYP2C9L3MBTL1GAANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |