Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31271389 | 0.92 | GPR119 (0.59) | GPR119CHRM2CHRM1CHRM3RET | |
| SCHEMBL24467795 | 0.86 | GPR119 (0.55) | GPR119CHRM2CHRM1CHRM3RET | |
| SCHEMBL24467778 | 0.86 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL25309274 | 0.85 | GPR119 (0.52) | GPR119CHRM2CHRM1CHRM3RET | |
| SCHEMBL29567107 | 0.84 | RET (0.52) | GPR119CHRM2CHRM1CHRM3RET | |
| SCHEMBL21909144 | 0.84 | RET (0.52) | GPR119CHRM2CHRM1CHRM3RET | |
| SCHEMBL24240917 | 0.84 | RET (0.52) | GPR119CHRM2CHRM1CHRM3RET | |
| SCHEMBL22720768 | 0.81 | GPR119 (0.50) | GPR119ACACBKCNK3KCNK9 | |
| SCHEMBL22660531 | 0.80 | GPR119 (0.45) | GPR119CHRM2CHRM1CHRM3RET | |
| SCHEMBL22516882 | 0.80 | RET (0.47) | GPR119CHRM2CHRM1CHRM3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |